- 9 Chickweed Lane by Brooke McEldowney
- B.C. by Johnny Hart
- Betty by Delainey & Rasmussen
- The Buckets by Greg Cravens
- Get Fuzzy by Darby Conley
- The Grizzwells by Bill Schorr
- Over The Hedge by Michael Fry and T Lewis
- Pearls Before Swine by Stephan Pastis
- Rose Is Rose by Don Wimmer, created by Pat Brady
- Dilbert by Scott Adams
- Sinfest by Tatsuya Ishida
- Mutts by Patrick McDonnell
Weekly or less
- Sequential Art by Phillip M. Jackson — Updates anywhere from monthly to whenever.
- Suihira: The City of Water by Riana Dorsey — Updates on Wednesdays.
- The Abominable Charles Christopher by Karl Kerschl — This one appears to be on a hiatus of sorts, most likely due to the artist being absorbed in other creative projects.
- Scandinavia and the World by Humon
Other / Discontinued
- The Devil’s Panties by Jennie and Obby Breeden – Updates on weekdays and sometimes on weekends)
- Oglaf – Updates Sundays (nsfw)
- Sabrina Online by Eric W. Schwartz — Ran from September 1996 until December 2016 with monthly installations of 3-4 strips.
- Pants Are Overrated — Ran from April 2009 until October 2011. Included here especially for the Calvin & Hobbes spin-offs.